ameras: Analyze Multiple Exposure Realizations in Association Studies

Analyze association studies with multiple realizations of a noisy or uncertain exposure. These can be obtained from e.g. a two-dimensional Monte Carlo dosimetry system (Simon et al 2015 <doi:10.1667/RR13729.1>) to characterize exposure uncertainty. The implemented methods are regression calibration (Carroll et al. 2006 <doi:10.1201/9781420010138>), extended regression calibration (Little et al. 2023 <doi:10.1038/s41598-023-42283-y>), Monte Carlo maximum likelihood (Stayner et al. 2007 <doi:10.1667/RR0677.1>), frequentist model averaging (Kwon et al. 2023 <doi:10.1371/journal.pone.0290498>), and Bayesian model averaging (Kwon et al. 2016 <doi:10.1002/sim.6635>). Supported model families are Gaussian, binomial, multinomial, Poisson, proportional hazards, and conditional logistic.

Version: 0.1.1
Depends: R (≥ 3.5.0), stats, nimble
Imports: Rcpp (≥ 1.0.10), RcppEigen, coda, numDeriv, MCMCvis, mvtnorm, memoise, methods
LinkingTo: Rcpp, RcppEigen
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0), ggplot2
Published: 2026-03-29
DOI: 10.32614/CRAN.package.ameras (may not be active yet)
Author: Sander Roberti ORCID iD [aut, cre], William Wheeler [aut], Deukwoo Kwon ORCID iD [aut], Ruth Pfeiffer ORCID iD [ctb], NCI [cph, fnd]
Maintainer: Sander Roberti <sander.roberti at nih.gov>
License: MIT + file LICENSE
NeedsCompilation: yes
Materials: README, NEWS
CRAN checks: ameras results

Documentation:

Reference manual: ameras.html , ameras.pdf
Vignettes: Confidence intervals (source, R code)
Fitting models and displaying output (source, R code)
Relative risk models (source, R code)
Parameter transformations (source, R code)

Downloads:

Package source: ameras_0.1.1.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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