TAP complexes           package:apComplex           R Documentation

_T_A_P _d_a_t_a _c_o_m_p_l_e_x _e_s_t_i_m_a_t_e_s

_D_e_s_c_r_i_p_t_i_o_n:

     Affiliation matrices with rows corresponding to proteins and
     columns corresponding to complexes.

_U_s_a_g_e:

     data(MBMEcTAP)
     data(SBMHcTAP)
     data(UnRBBcTAP)

_D_e_t_a_i_l_s:

     These are the results from an analysis of the TAP data (Gavin et
     al., 2002) using the Protein Complex Membership Graph (PCMG)
     algorithm proposed by Scholtens and Gentleman (2004).  These
     estimates were constructed using a sensitivity parameter of .75,
     specificity of .995, and external data based on Gene Ontology
     cellular component annotation.

     'MBMEcTAP' contains multi-bait-multi-edge complex estimates. 
     'SBMHcTAP' contains single-bait-multi-hit complex estimates. 
     'UnRBBcTAP' contains unreciprocated bait-bait complex estimates.

_S_o_u_r_c_e:

     Scholtens, D. and Gentleman, R.  Making sense of high throughput
     protein-protein interaction data. (2004).

_R_e_f_e_r_e_n_c_e_s:

     Gavin, et al. Functional organization of the yeast proteome by
     systematic analysis of protein complexes.  Nature 415, 141-147
     (2002).

_E_x_a_m_p_l_e_s:

     data(MBMEcTAP)

