HMSPCI complexes          package:apComplex          R Documentation

_H_M_S_P_C_I _d_a_t_a _c_o_m_p_l_e_x _e_s_t_i_m_a_t_e_s

_D_e_s_c_r_i_p_t_i_o_n:

     Affiliation matrices with rows corresponding to proteins and
     columns corresponding to complexes.

_U_s_a_g_e:

     data(MBMEcHMSPCI)
     data(SBMHcHMSPCI)
     data(UnRBBcHMSPCI)

_D_e_t_a_i_l_s:

     These are the results from an analysis of the HMS-PCI data (Ho et
     al., 2002) using the Protein Complex Membership Graph (PCMG)
     algorithm proposed by Scholtens and Gentleman (2004).  These
     estimates were constructed using a sensitivity parameter of .75,
     specificity of .99, and external data based on Gene Ontology
     cellular component annotation.

     'MBMEcHMSPCI' contains multi-bait-multi-edge complex estimates. 
     'SBMHcHMSPCI' contains single-bait-multi-hit complex estimates. 
     'UnRBBcHMSPCI' contains unreciprocated bait-bait complex
     estimates.

_S_o_u_r_c_e:

     Scholtens, D. and Gentleman, R.  Making sense of high throughput
     protein-protein interaction data. (2004).

_R_e_f_e_r_e_n_c_e_s:

     Ho, et al. Systematic identification of protein complexes in
     Saccharomyces cerevisiae by mass spectrometry.  Nature 415,
     180-183 (2002).

_E_x_a_m_p_l_e_s:

     data(MBMEcHMSPCI)

