drugTargetInteractions-package {drugTargetInteractions} | R Documentation |
The drugTargetInteractions package provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database.
The DESCRIPTION file:
Package: | drugTargetInteractions |
Type: | Package |
Title: | Drug-Target Interactions |
Version: | 1.0.0 |
Date: | 2021-03-22 |
Authors@R: | person("Thomas", "Girke", email="thomas.girke@ucr.edu", role=c("cre", "aut")) |
Description: | Provides utilities for identifying drug-target interactions for sets of small molecule or gene/protein identifiers. The required drug-target interaction information is obained from a local SQLite instance of the ChEMBL database. ChEMBL has been chosen for this purpose, because it provides one of the most comprehensive and best annotatated knowledge resources for drug-target information available in the public domain. |
Depends: | methods, R (>= 4.1) |
Imports: | utils, RSQLite, UniProt.ws, biomaRt,ensembldb, BiocFileCache,dplyr,rappdirs, AnnotationFilter, S4Vectors |
Suggests: | RUnit, BiocStyle, knitr, rmarkdown, ggplot2, reshape2, DT, EnsDb.Hsapiens.v86 |
VignetteBuilder: | knitr |
License: | Artistic-2.0 |
NeedsCompilation: | no |
URL: | https://github.com/longevity-consortium/LC_Chemoinformatics |
biocViews: | Cheminformatics, BiomedicalInformatics, Pharmacogenetics, Pharmacogenomics, Proteomics, Metabolomics |
RoxygenNote: | 7.1.1 |
BugReports: | https://github.com/girke-lab/drugTargetInteractions |
git_url: | https://git.bioconductor.org/packages/drugTargetInteractions |
git_branch: | RELEASE_3_13 |
git_last_commit: | be807a4 |
git_last_commit_date: | 2021-05-19 |
Date/Publication: | 2021-05-19 |
Author: | Thomas Girke [cre, aut] |
Maintainer: | Thomas Girke <thomas.girke@ucr.edu> |
Index of help topics:
cmpIdMapping cmpIdMapping downloadChemblDb downloadChemblDb downloadUniChem downloadUniChem drugTargetAnnot drugTargetAnnot drugTargetAnnotTable drugTargetAnnotTable drugTargetBioactivity drugTargetBioactivity drugTargetInteractions-package Drug-Target Interactions genConfig genConfig getDrugTarget getDrugTarget getParalogs getParalogs getSymEnsUp Gene to Protein ID Mappings getUniprotIDs Retrieve UniProt IDs via ID and Cluster Mappings processDrugage processDrugage runDrugTarget_Annot_Bioassay runDrugTarget_Annot_Bioassay transformTTD transformTTD
NA
Maintainer: NA